In the two-group classification, AML samples are basically clustered together tightly no matter rows are scaled are not. The big overlap between also due to the difference between AML samples and ALL samples or at least a subset of ALL samples. As we observed from cola results, samples can also be separated into three groups where ALL samples are separated into two groups.
In the three-group classification, when rows are scaled, only ATC:skmeans generates stable partition with 1-PAC score 0.96, while when rows are not scaled, none method generates stable partition.
Figure 8A. Consensus heatmaps with k = 3
Figure 8B. Consensus heatmaps with k = 3
We pick the three-group classification from ATC:skmeans for the scaled case, and … On the other hand, the original Golub study classify ALL samples into B-cell and T-cell groups by SOM method. Note their method was applied on the whole expression matrix that are not scaled.
Figure 10.
The two classifications are both separated…
Figure 11A
Figure 11B
The overlap between the two sets of classification becomes large. We .. it due to the difference from AML group.
For the classification.. we removed the samples with label 1 in either classifications. ANd we applied t-test between group 2 and group 3 …
Figure 13.
If look at the overlap between … the two sets are quite exclusive.
Figure 14
Since now the two sets of signatures are … we next check the biological functions that are enriched in the two sets of genes.
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0009725 | response to hormone | 108/966 | 920/17913 | 0e+00 | 0.0000 | 108 |
| GO:0010243 | response to organonitrogen compound | 107/966 | 932/17913 | 0e+00 | 0.0000 | 107 |
| GO:1901699 | cellular response to nitrogen compound | 80/966 | 620/17913 | 0e+00 | 0.0000 | 80 |
| GO:0071417 | cellular response to organonitrogen compound | 73/966 | 559/17913 | 0e+00 | 0.0000 | 73 |
| GO:0044419 | interspecies interaction between organisms | 102/966 | 928/17913 | 0e+00 | 0.0000 | 102 |
| GO:0016071 | mRNA metabolic process | 92/966 | 815/17913 | 0e+00 | 0.0000 | 92 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 103/966 | 968/17913 | 0e+00 | 0.0000 | 103 |
| GO:0014070 | response to organic cyclic compound | 96/966 | 879/17913 | 0e+00 | 0.0000 | 96 |
| GO:0033993 | response to lipid | 96/966 | 884/17913 | 0e+00 | 0.0000 | 96 |
| GO:0044403 | symbiont process | 96/966 | 884/17913 | 0e+00 | 0.0000 | 96 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 79/966 | 669/17913 | 0e+00 | 0.0000 | 79 |
| GO:0051050 | positive regulation of transport | 100/966 | 942/17913 | 0e+00 | 0.0000 | 100 |
| GO:0032870 | cellular response to hormone stimulus | 77/966 | 647/17913 | 0e+00 | 0.0000 | 77 |
| GO:0042493 | response to drug | 101/966 | 958/17913 | 0e+00 | 0.0000 | 101 |
| GO:0019725 | cellular homeostasis | 90/966 | 814/17913 | 0e+00 | 0.0000 | 90 |
| GO:0016032 | viral process | 90/966 | 822/17913 | 0e+00 | 0.0000 | 90 |
| GO:1901652 | response to peptide | 61/966 | 491/17913 | 0e+00 | 0.0000 | 61 |
| GO:0009894 | regulation of catabolic process | 94/966 | 916/17913 | 0e+00 | 0.0000 | 94 |
| GO:0036293 | response to decreased oxygen levels | 50/966 | 365/17913 | 0e+00 | 0.0000 | 50 |
| GO:0001666 | response to hypoxia | 49/966 | 354/17913 | 0e+00 | 0.0000 | 49 |
| GO:0070482 | response to oxygen levels | 52/966 | 389/17913 | 0e+00 | 0.0000 | 52 |
| GO:0008380 | RNA splicing | 56/966 | 440/17913 | 0e+00 | 0.0000 | 56 |
| GO:0031329 | regulation of cellular catabolic process | 85/966 | 814/17913 | 0e+00 | 0.0000 | 85 |
| GO:1901653 | cellular response to peptide | 49/966 | 364/17913 | 0e+00 | 0.0000 | 49 |
| GO:0019221 | cytokine-mediated signaling pathway | 81/966 | 764/17913 | 0e+00 | 0.0000 | 81 |
| GO:0042327 | positive regulation of phosphorylation | 95/966 | 955/17913 | 0e+00 | 0.0000 | 95 |
| GO:0048534 | hematopoietic or lymphoid organ development | 90/966 | 890/17913 | 0e+00 | 0.0000 | 90 |
| GO:0009611 | response to wounding | 73/966 | 665/17913 | 0e+00 | 0.0000 | 73 |
| GO:0000165 | MAPK cascade | 89/966 | 882/17913 | 0e+00 | 0.0000 | 89 |
| GO:0051169 | nuclear transport | 43/966 | 305/17913 | 0e+00 | 0.0000 | 43 |
| GO:0002520 | immune system development | 93/966 | 938/17913 | 0e+00 | 0.0000 | 93 |
| GO:0023014 | signal transduction by protein phosphorylation | 89/966 | 886/17913 | 0e+00 | 0.0000 | 89 |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 24/966 | 115/17913 | 0e+00 | 0.0000 | 24 |
| GO:1903311 | regulation of mRNA metabolic process | 40/966 | 275/17913 | 0e+00 | 0.0000 | 40 |
| GO:1903530 | regulation of secretion by cell | 75/966 | 703/17913 | 0e+00 | 0.0000 | 75 |
| GO:0051046 | regulation of secretion | 79/966 | 757/17913 | 0e+00 | 0.0000 | 79 |
| GO:0055082 | cellular chemical homeostasis | 72/966 | 666/17913 | 0e+00 | 0.0000 | 72 |
| GO:0006913 | nucleocytoplasmic transport | 42/966 | 302/17913 | 0e+00 | 0.0000 | 42 |
| GO:0000375 | RNA splicing, via transesterification reactions | 46/966 | 348/17913 | 0e+00 | 0.0000 | 46 |
| GO:0006886 | intracellular protein transport | 84/966 | 833/17913 | 0e+00 | 0.0000 | 84 |
| GO:0030097 | hemopoiesis | 85/966 | 847/17913 | 0e+00 | 0.0000 | 85 |
| GO:0007417 | central nervous system development | 91/966 | 935/17913 | 0e+00 | 0.0000 | 91 |
| GO:0006397 | mRNA processing | 58/966 | 499/17913 | 0e+00 | 0.0000 | 58 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 45/966 | 344/17913 | 0e+00 | 0.0000 | 45 |
| GO:0000398 | mRNA splicing, via spliceosome | 45/966 | 344/17913 | 0e+00 | 0.0000 | 45 |
| GO:0048511 | rhythmic process | 40/966 | 287/17913 | 0e+00 | 0.0000 | 40 |
| GO:0033238 | regulation of cellular amine metabolic process | 19/966 | 80/17913 | 0e+00 | 0.0000 | 19 |
| GO:0060341 | regulation of cellular localization | 85/966 | 863/17913 | 0e+00 | 0.0000 | 85 |
| GO:0001934 | positive regulation of protein phosphorylation | 88/966 | 907/17913 | 0e+00 | 0.0000 | 88 |
| GO:0048732 | gland development | 51/966 | 422/17913 | 0e+00 | 0.0000 | 51 |
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 22/966 | 109/17913 | 0e+00 | 0.0000 | 22 |
| GO:0060322 | head development | 75/966 | 738/17913 | 0e+00 | 0.0000 | 75 |
| GO:0033674 | positive regulation of kinase activity | 60/966 | 541/17913 | 0e+00 | 0.0000 | 60 |
| GO:0006887 | exocytosis | 84/966 | 862/17913 | 0e+00 | 0.0000 | 84 |
| GO:0046883 | regulation of hormone secretion | 36/966 | 254/17913 | 0e+00 | 0.0000 | 36 |
| GO:0050852 | T cell receptor signaling pathway | 29/966 | 180/17913 | 0e+00 | 0.0000 | 29 |
| GO:0023061 | signal release | 51/966 | 433/17913 | 0e+00 | 0.0000 | 51 |
| GO:1905330 | regulation of morphogenesis of an epithelium | 29/966 | 181/17913 | 0e+00 | 0.0000 | 29 |
| GO:0090087 | regulation of peptide transport | 72/966 | 706/17913 | 0e+00 | 0.0000 | 72 |
| GO:0002444 | myeloid leukocyte mediated immunity | 60/966 | 549/17913 | 0e+00 | 0.0000 | 60 |
| GO:0043069 | negative regulation of programmed cell death | 87/966 | 916/17913 | 0e+00 | 0.0000 | 87 |
| GO:0048545 | response to steroid hormone | 46/966 | 375/17913 | 0e+00 | 0.0000 | 46 |
| GO:0098657 | import into cell | 75/966 | 751/17913 | 0e+00 | 0.0000 | 75 |
| GO:0002283 | neutrophil activation involved in immune response | 55/966 | 488/17913 | 0e+00 | 0.0000 | 55 |
| GO:0050778 | positive regulation of immune response | 79/966 | 809/17913 | 0e+00 | 0.0000 | 79 |
| GO:0043066 | negative regulation of apoptotic process | 85/966 | 894/17913 | 0e+00 | 0.0000 | 85 |
| GO:2000027 | regulation of animal organ morphogenesis | 35/966 | 250/17913 | 0e+00 | 0.0000 | 35 |
| GO:0043434 | response to peptide hormone | 48/966 | 404/17913 | 0e+00 | 0.0000 | 48 |
| GO:0051347 | positive regulation of transferase activity | 64/966 | 609/17913 | 0e+00 | 0.0000 | 64 |
| GO:0051098 | regulation of binding | 45/966 | 368/17913 | 0e+00 | 0.0000 | 45 |
| GO:0071375 | cellular response to peptide hormone stimulus | 39/966 | 297/17913 | 0e+00 | 0.0000 | 39 |
| GO:0006457 | protein folding | 28/966 | 176/17913 | 0e+00 | 0.0000 | 28 |
| GO:0007409 | axonogenesis | 47/966 | 393/17913 | 0e+00 | 0.0000 | 47 |
| GO:0009266 | response to temperature stimulus | 32/966 | 219/17913 | 0e+00 | 0.0000 | 32 |
| GO:0006836 | neurotransmitter transport | 34/966 | 241/17913 | 0e+00 | 0.0000 | 34 |
| GO:0030072 | peptide hormone secretion | 34/966 | 241/17913 | 0e+00 | 0.0000 | 34 |
| GO:0032101 | regulation of response to external stimulus | 83/966 | 873/17913 | 0e+00 | 0.0000 | 83 |
| GO:0007420 | brain development | 70/966 | 694/17913 | 0e+00 | 0.0000 | 70 |
| GO:0090276 | regulation of peptide hormone secretion | 30/966 | 199/17913 | 0e+00 | 0.0000 | 30 |
| GO:0009308 | amine metabolic process | 23/966 | 128/17913 | 0e+00 | 0.0000 | 23 |
| GO:0006974 | cellular response to DNA damage stimulus | 77/966 | 791/17913 | 0e+00 | 0.0000 | 77 |
| GO:0008015 | blood circulation | 57/966 | 523/17913 | 0e+00 | 0.0000 | 57 |
| GO:0009408 | response to heat | 26/966 | 158/17913 | 0e+00 | 0.0000 | 26 |
| GO:0043488 | regulation of mRNA stability | 26/966 | 158/17913 | 0e+00 | 0.0000 | 26 |
| GO:0017144 | drug metabolic process | 77/966 | 792/17913 | 0e+00 | 0.0000 | 77 |
| GO:0043312 | neutrophil degranulation | 54/966 | 485/17913 | 0e+00 | 0.0000 | 54 |
| GO:0046879 | hormone secretion | 39/966 | 301/17913 | 0e+00 | 0.0000 | 39 |
| GO:0002446 | neutrophil mediated immunity | 55/966 | 499/17913 | 0e+00 | 0.0000 | 55 |
| GO:0042119 | neutrophil activation | 55/966 | 499/17913 | 0e+00 | 0.0000 | 55 |
| GO:0050878 | regulation of body fluid levels | 55/966 | 499/17913 | 0e+00 | 0.0000 | 55 |
| GO:0061564 | axon development | 50/966 | 438/17913 | 0e+00 | 0.0000 | 50 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 32/966 | 224/17913 | 0e+00 | 0.0000 | 32 |
| GO:0010720 | positive regulation of cell development | 57/966 | 528/17913 | 0e+00 | 0.0000 | 57 |
| GO:0044106 | cellular amine metabolic process | 22/966 | 121/17913 | 0e+00 | 0.0000 | 22 |
| GO:0043408 | regulation of MAPK cascade | 69/966 | 689/17913 | 0e+00 | 0.0000 | 69 |
| GO:0044706 | multi-multicellular organism process | 32/966 | 225/17913 | 0e+00 | 0.0000 | 32 |
| GO:0001101 | response to acid chemical | 41/966 | 330/17913 | 0e+00 | 0.0000 | 41 |
| GO:0030003 | cellular cation homeostasis | 56/966 | 518/17913 | 0e+00 | 0.0000 | 56 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 17/966 | 77/17913 | 0e+00 | 0.0000 | 17 |
| GO:0003013 | circulatory system process | 57/966 | 532/17913 | 0e+00 | 0.0000 | 57 |
| GO:0036230 | granulocyte activation | 55/966 | 506/17913 | 0e+00 | 0.0000 | 55 |
| GO:0043269 | regulation of ion transport | 65/966 | 639/17913 | 0e+00 | 0.0000 | 65 |
| GO:0043487 | regulation of RNA stability | 26/966 | 163/17913 | 0e+00 | 0.0000 | 26 |
| GO:0009887 | animal organ morphogenesis | 90/966 | 989/17913 | 0e+00 | 0.0000 | 90 |
| GO:0071396 | cellular response to lipid | 60/966 | 576/17913 | 0e+00 | 0.0000 | 60 |
| GO:0045087 | innate immune response | 83/966 | 893/17913 | 0e+00 | 0.0000 | 83 |
| GO:0009914 | hormone transport | 39/966 | 311/17913 | 0e+00 | 0.0000 | 39 |
| GO:0051170 | import into nucleus | 22/966 | 125/17913 | 0e+00 | 0.0000 | 22 |
| GO:0080135 | regulation of cellular response to stress | 70/966 | 713/17913 | 0e+00 | 0.0000 | 70 |
| GO:0035567 | non-canonical Wnt signaling pathway | 24/966 | 145/17913 | 0e+00 | 0.0000 | 24 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 27/966 | 176/17913 | 0e+00 | 0.0000 | 27 |
| GO:0097190 | apoptotic signaling pathway | 60/966 | 579/17913 | 0e+00 | 0.0000 | 60 |
| GO:0033365 | protein localization to organelle | 76/966 | 798/17913 | 0e+00 | 0.0000 | 76 |
| GO:0002253 | activation of immune response | 65/966 | 647/17913 | 0e+00 | 0.0000 | 65 |
| GO:0045860 | positive regulation of protein kinase activity | 54/966 | 501/17913 | 0e+00 | 0.0000 | 54 |
| GO:0003006 | developmental process involved in reproduction | 65/966 | 649/17913 | 0e+00 | 0.0001 | 65 |
| GO:0002275 | myeloid cell activation involved in immune response | 57/966 | 542/17913 | 0e+00 | 0.0001 | 57 |
| GO:0002790 | peptide secretion | 60/966 | 582/17913 | 0e+00 | 0.0001 | 60 |
| GO:0015696 | ammonium transport | 17/966 | 81/17913 | 0e+00 | 0.0001 | 17 |
| GO:0006873 | cellular ion homeostasis | 56/966 | 531/17913 | 0e+00 | 0.0001 | 56 |
| GO:0043299 | leukocyte degranulation | 56/966 | 532/17913 | 0e+00 | 0.0001 | 56 |
| GO:0045597 | positive regulation of cell differentiation | 87/966 | 962/17913 | 0e+00 | 0.0001 | 87 |
| GO:0050769 | positive regulation of neurogenesis | 50/966 | 455/17913 | 0e+00 | 0.0001 | 50 |
| GO:0070201 | regulation of establishment of protein localization | 70/966 | 723/17913 | 0e+00 | 0.0001 | 70 |
| GO:0040008 | regulation of growth | 66/966 | 668/17913 | 0e+00 | 0.0001 | 66 |
| GO:0006259 | DNA metabolic process | 87/966 | 964/17913 | 0e+00 | 0.0001 | 87 |
| GO:0032880 | regulation of protein localization | 88/966 | 979/17913 | 0e+00 | 0.0001 | 88 |
| GO:0043549 | regulation of kinase activity | 76/966 | 808/17913 | 0e+00 | 0.0001 | 76 |
| GO:0055080 | cation homeostasis | 60/966 | 588/17913 | 0e+00 | 0.0001 | 60 |
| GO:0071453 | cellular response to oxygen levels | 32/966 | 237/17913 | 0e+00 | 0.0001 | 32 |
| GO:0045055 | regulated exocytosis | 73/966 | 768/17913 | 0e+00 | 0.0001 | 73 |
| GO:1901361 | organic cyclic compound catabolic process | 67/966 | 685/17913 | 0e+00 | 0.0001 | 67 |
| GO:0007565 | female pregnancy | 28/966 | 193/17913 | 0e+00 | 0.0001 | 28 |
| GO:0001819 | positive regulation of cytokine production | 49/966 | 446/17913 | 0e+00 | 0.0001 | 49 |
| GO:0009991 | response to extracellular stimulus | 53/966 | 498/17913 | 0e+00 | 0.0001 | 53 |
| GO:0009755 | hormone-mediated signaling pathway | 30/966 | 216/17913 | 0e+00 | 0.0001 | 30 |
| GO:0009636 | response to toxic substance | 53/966 | 499/17913 | 0e+00 | 0.0001 | 53 |
| GO:0051100 | negative regulation of binding | 25/966 | 162/17913 | 0e+00 | 0.0001 | 25 |
| GO:0032868 | response to insulin | 33/966 | 252/17913 | 0e+00 | 0.0001 | 33 |
| GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 26/966 | 174/17913 | 0e+00 | 0.0001 | 26 |
| GO:0009895 | negative regulation of catabolic process | 36/966 | 288/17913 | 0e+00 | 0.0001 | 36 |
| GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 17/966 | 85/17913 | 0e+00 | 0.0001 | 17 |
| GO:0048608 | reproductive structure development | 47/966 | 426/17913 | 0e+00 | 0.0001 | 47 |
| GO:0034655 | nucleobase-containing compound catabolic process | 60/966 | 598/17913 | 0e+00 | 0.0001 | 60 |
| GO:0034976 | response to endoplasmic reticulum stress | 33/966 | 254/17913 | 0e+00 | 0.0001 | 33 |
| GO:0006352 | DNA-templated transcription, initiation | 31/966 | 231/17913 | 0e+00 | 0.0001 | 31 |
| GO:0019882 | antigen processing and presentation | 30/966 | 220/17913 | 0e+00 | 0.0001 | 30 |
| GO:0036294 | cellular response to decreased oxygen levels | 30/966 | 220/17913 | 0e+00 | 0.0001 | 30 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 18/966 | 95/17913 | 0e+00 | 0.0001 | 18 |
| GO:0031667 | response to nutrient levels | 50/966 | 466/17913 | 0e+00 | 0.0001 | 50 |
| GO:0098771 | inorganic ion homeostasis | 60/966 | 600/17913 | 0e+00 | 0.0001 | 60 |
| GO:0046700 | heterocycle catabolic process | 63/966 | 641/17913 | 0e+00 | 0.0001 | 63 |
| GO:0071407 | cellular response to organic cyclic compound | 55/966 | 533/17913 | 0e+00 | 0.0001 | 55 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 39/966 | 328/17913 | 0e+00 | 0.0001 | 39 |
| GO:0071456 | cellular response to hypoxia | 29/966 | 210/17913 | 0e+00 | 0.0001 | 29 |
| GO:0061458 | reproductive system development | 47/966 | 429/17913 | 0e+00 | 0.0001 | 47 |
| GO:0050767 | regulation of neurogenesis | 72/966 | 768/17913 | 0e+00 | 0.0001 | 72 |
| GO:0048002 | antigen processing and presentation of peptide antigen | 27/966 | 188/17913 | 0e+00 | 0.0001 | 27 |
| GO:0006521 | regulation of cellular amino acid metabolic process | 14/966 | 61/17913 | 0e+00 | 0.0001 | 14 |
| GO:0002764 | immune response-regulating signaling pathway | 60/966 | 603/17913 | 0e+00 | 0.0001 | 60 |
| GO:0061013 | regulation of mRNA catabolic process | 26/966 | 178/17913 | 0e+00 | 0.0001 | 26 |
| GO:0034504 | protein localization to nucleus | 30/966 | 223/17913 | 0e+00 | 0.0001 | 30 |
| GO:0007568 | aging | 38/966 | 318/17913 | 0e+00 | 0.0001 | 38 |
| GO:0008284 | positive regulation of cell proliferation | 83/966 | 931/17913 | 0e+00 | 0.0001 | 83 |
| GO:0048729 | tissue morphogenesis | 62/966 | 635/17913 | 0e+00 | 0.0001 | 62 |
| GO:0016579 | protein deubiquitination | 33/966 | 260/17913 | 0e+00 | 0.0001 | 33 |
| GO:0002757 | immune response-activating signal transduction | 57/966 | 567/17913 | 0e+00 | 0.0001 | 57 |
| GO:0030522 | intracellular receptor signaling pathway | 34/966 | 272/17913 | 0e+00 | 0.0001 | 34 |
| GO:0034612 | response to tumor necrosis factor | 35/966 | 284/17913 | 0e+00 | 0.0001 | 35 |
| GO:0045859 | regulation of protein kinase activity | 69/966 | 733/17913 | 0e+00 | 0.0001 | 69 |
| GO:0048863 | stem cell differentiation | 31/966 | 237/17913 | 0e+00 | 0.0002 | 31 |
| GO:0001505 | regulation of neurotransmitter levels | 38/966 | 321/17913 | 0e+00 | 0.0002 | 38 |
| GO:0070646 | protein modification by small protein removal | 34/966 | 273/17913 | 0e+00 | 0.0002 | 34 |
| GO:0002274 | myeloid leukocyte activation | 63/966 | 652/17913 | 0e+00 | 0.0002 | 63 |
| GO:0031175 | neuron projection development | 79/966 | 879/17913 | 0e+00 | 0.0002 | 79 |
| GO:0042593 | glucose homeostasis | 30/966 | 227/17913 | 0e+00 | 0.0002 | 30 |
| GO:0008285 | negative regulation of cell proliferation | 70/966 | 751/17913 | 0e+00 | 0.0002 | 70 |
| GO:1902036 | regulation of hematopoietic stem cell differentiation | 15/966 | 72/17913 | 0e+00 | 0.0002 | 15 |
| GO:0031145 | anaphase-promoting complex-dependent catabolic process | 16/966 | 81/17913 | 0e+00 | 0.0002 | 16 |
| GO:0033500 | carbohydrate homeostasis | 30/966 | 228/17913 | 0e+00 | 0.0002 | 30 |
| GO:0032386 | regulation of intracellular transport | 44/966 | 400/17913 | 0e+00 | 0.0002 | 44 |
| GO:0019439 | aromatic compound catabolic process | 63/966 | 655/17913 | 0e+00 | 0.0002 | 63 |
| GO:0044270 | cellular nitrogen compound catabolic process | 62/966 | 642/17913 | 0e+00 | 0.0002 | 62 |
| GO:0099536 | synaptic signaling | 59/966 | 601/17913 | 0e+00 | 0.0002 | 59 |
| GO:0060627 | regulation of vesicle-mediated transport | 50/966 | 480/17913 | 0e+00 | 0.0002 | 50 |
| GO:0006875 | cellular metal ion homeostasis | 49/966 | 467/17913 | 0e+00 | 0.0002 | 49 |
| GO:0001944 | vasculature development | 72/966 | 784/17913 | 0e+00 | 0.0002 | 72 |
| GO:0030163 | protein catabolic process | 73/966 | 799/17913 | 0e+00 | 0.0002 | 73 |
| GO:0002443 | leukocyte mediated immunity | 74/966 | 814/17913 | 0e+00 | 0.0002 | 74 |
| GO:0051090 | regulation of DNA-binding transcription factor activity | 46/966 | 429/17913 | 0e+00 | 0.0002 | 46 |
| GO:0001525 | angiogenesis | 57/966 | 576/17913 | 0e+00 | 0.0002 | 57 |
| GO:0043270 | positive regulation of ion transport | 33/966 | 266/17913 | 0e+00 | 0.0002 | 33 |
| GO:0071356 | cellular response to tumor necrosis factor | 33/966 | 266/17913 | 0e+00 | 0.0002 | 33 |
| GO:0000904 | cell morphogenesis involved in differentiation | 61/966 | 632/17913 | 0e+00 | 0.0002 | 61 |
| GO:0002791 | regulation of peptide secretion | 50/966 | 483/17913 | 0e+00 | 0.0002 | 50 |
| GO:0000902 | cell morphogenesis | 78/966 | 874/17913 | 0e+00 | 0.0002 | 78 |
| GO:0032869 | cellular response to insulin stimulus | 27/966 | 197/17913 | 0e+00 | 0.0002 | 27 |
| GO:0060218 | hematopoietic stem cell differentiation | 16/966 | 83/17913 | 0e+00 | 0.0002 | 16 |
| GO:0032735 | positive regulation of interleukin-12 production | 10/966 | 34/17913 | 0e+00 | 0.0002 | 10 |
| GO:0051223 | regulation of protein transport | 64/966 | 677/17913 | 0e+00 | 0.0002 | 64 |
| GO:0045333 | cellular respiration | 25/966 | 176/17913 | 0e+00 | 0.0003 | 25 |
| GO:0019373 | epoxygenase P450 pathway | 6/966 | 11/17913 | 0e+00 | 0.0003 | 6 |
| GO:0060284 | regulation of cell development | 79/966 | 893/17913 | 0e+00 | 0.0003 | 79 |
| GO:0072358 | cardiovascular system development | 72/966 | 792/17913 | 0e+00 | 0.0003 | 72 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 15/966 | 75/17913 | 0e+00 | 0.0003 | 15 |
| GO:0045664 | regulation of neuron differentiation | 59/966 | 609/17913 | 0e+00 | 0.0003 | 59 |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | 51/966 | 500/17913 | 0e+00 | 0.0003 | 51 |
| GO:0010498 | proteasomal protein catabolic process | 42/966 | 382/17913 | 0e+00 | 0.0003 | 42 |
| GO:0010948 | negative regulation of cell cycle process | 39/966 | 344/17913 | 0e+00 | 0.0003 | 39 |
| GO:0051047 | positive regulation of secretion | 44/966 | 409/17913 | 0e+00 | 0.0003 | 44 |
| GO:0030073 | insulin secretion | 27/966 | 200/17913 | 0e+00 | 0.0003 | 27 |
| GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 16/966 | 85/17913 | 0e+00 | 0.0003 | 16 |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | 24/966 | 167/17913 | 0e+00 | 0.0003 | 24 |
| GO:0098810 | neurotransmitter reuptake | 8/966 | 22/17913 | 0e+00 | 0.0003 | 8 |
| GO:0045786 | negative regulation of cell cycle | 59/966 | 613/17913 | 0e+00 | 0.0003 | 59 |
| GO:0050801 | ion homeostasis | 63/966 | 669/17913 | 0e+00 | 0.0003 | 63 |
| GO:0055065 | metal ion homeostasis | 53/966 | 531/17913 | 0e+00 | 0.0003 | 53 |
| GO:0006520 | cellular amino acid metabolic process | 39/966 | 347/17913 | 0e+00 | 0.0003 | 39 |
| GO:0048514 | blood vessel morphogenesis | 63/966 | 670/17913 | 0e+00 | 0.0003 | 63 |
| GO:0048013 | ephrin receptor signaling pathway | 16/966 | 86/17913 | 0e+00 | 0.0003 | 16 |
| GO:0009615 | response to virus | 37/966 | 323/17913 | 0e+00 | 0.0003 | 37 |
| GO:0009060 | aerobic respiration | 14/966 | 68/17913 | 0e+00 | 0.0003 | 14 |
| GO:0030001 | metal ion transport | 72/966 | 800/17913 | 0e+00 | 0.0003 | 72 |
| GO:0043902 | positive regulation of multi-organism process | 25/966 | 180/17913 | 0e+00 | 0.0003 | 25 |
| GO:0038095 | Fc-epsilon receptor signaling pathway | 24/966 | 169/17913 | 0e+00 | 0.0003 | 24 |
| GO:0051338 | regulation of transferase activity | 79/966 | 903/17913 | 0e+00 | 0.0003 | 79 |
| GO:0046794 | transport of virus | 13/966 | 60/17913 | 0e+00 | 0.0004 | 13 |
| GO:1903706 | regulation of hemopoiesis | 48/966 | 468/17913 | 0e+00 | 0.0004 | 48 |
| GO:0035239 | tube morphogenesis | 79/966 | 905/17913 | 0e+00 | 0.0004 | 79 |
| GO:0045471 | response to ethanol | 20/966 | 127/17913 | 0e+00 | 0.0004 | 20 |
| GO:0007268 | chemical synaptic transmission | 57/966 | 591/17913 | 0e+00 | 0.0004 | 57 |
| GO:0098916 | anterograde trans-synaptic signaling | 57/966 | 591/17913 | 0e+00 | 0.0004 | 57 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 15/966 | 78/17913 | 0e+00 | 0.0004 | 15 |
| GO:1902750 | negative regulation of cell cycle G2/M phase transition | 17/966 | 97/17913 | 0e+00 | 0.0004 | 17 |
| GO:0006935 | chemotaxis | 54/966 | 551/17913 | 0e+00 | 0.0004 | 54 |
| GO:0035821 | modification of morphology or physiology of other organism | 23/966 | 160/17913 | 0e+00 | 0.0004 | 23 |
| GO:0043393 | regulation of protein binding | 28/966 | 217/17913 | 0e+00 | 0.0004 | 28 |
| GO:0009607 | response to biotic stimulus | 81/966 | 938/17913 | 0e+00 | 0.0004 | 81 |
| GO:0070555 | response to interleukin-1 | 25/966 | 183/17913 | 0e+00 | 0.0004 | 25 |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 42/966 | 392/17913 | 0e+00 | 0.0004 | 42 |
| GO:0042330 | taxis | 54/966 | 553/17913 | 0e+00 | 0.0004 | 54 |
| GO:0043410 | positive regulation of MAPK cascade | 50/966 | 499/17913 | 0e+00 | 0.0004 | 50 |
| GO:0001816 | cytokine production | 69/966 | 765/17913 | 0e+00 | 0.0004 | 69 |
| GO:0001568 | blood vessel development | 68/966 | 751/17913 | 0e+00 | 0.0004 | 68 |
| GO:0099537 | trans-synaptic signaling | 57/966 | 596/17913 | 0e+00 | 0.0004 | 57 |
| GO:0006401 | RNA catabolic process | 40/966 | 368/17913 | 0e+00 | 0.0005 | 40 |
| GO:1903532 | positive regulation of secretion by cell | 41/966 | 381/17913 | 0e+00 | 0.0005 | 41 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 45/966 | 434/17913 | 0e+00 | 0.0005 | 45 |
| GO:0006936 | muscle contraction | 38/966 | 343/17913 | 0e+00 | 0.0005 | 38 |
| GO:0051960 | regulation of nervous system development | 76/966 | 870/17913 | 0e+00 | 0.0005 | 76 |
| GO:0006091 | generation of precursor metabolites and energy | 50/966 | 502/17913 | 0e+00 | 0.0005 | 50 |
| GO:0051952 | regulation of amine transport | 14/966 | 71/17913 | 0e+00 | 0.0005 | 14 |
| GO:0097305 | response to alcohol | 29/966 | 232/17913 | 0e+00 | 0.0005 | 29 |
| GO:0031330 | negative regulation of cellular catabolic process | 30/966 | 244/17913 | 0e+00 | 0.0005 | 30 |
| GO:0006954 | inflammatory response | 70/966 | 784/17913 | 0e+00 | 0.0005 | 70 |
| GO:0001817 | regulation of cytokine production | 64/966 | 698/17913 | 0e+00 | 0.0005 | 64 |
| GO:0007548 | sex differentiation | 32/966 | 269/17913 | 0e+00 | 0.0005 | 32 |
| GO:0019226 | transmission of nerve impulse | 12/966 | 54/17913 | 0e+00 | 0.0005 | 12 |
| GO:0015672 | monovalent inorganic cation transport | 48/966 | 477/17913 | 0e+00 | 0.0005 | 48 |
| GO:0051707 | response to other organism | 78/966 | 903/17913 | 0e+00 | 0.0005 | 78 |
| GO:0040007 | growth | 81/966 | 948/17913 | 0e+00 | 0.0005 | 81 |
| GO:0051962 | positive regulation of nervous system development | 51/966 | 519/17913 | 0e+00 | 0.0006 | 51 |
| GO:0043207 | response to external biotic stimulus | 78/966 | 905/17913 | 0e+00 | 0.0006 | 78 |
| GO:0072507 | divalent inorganic cation homeostasis | 43/966 | 412/17913 | 0e+00 | 0.0006 | 43 |
| GO:0072594 | establishment of protein localization to organelle | 46/966 | 452/17913 | 0e+00 | 0.0006 | 46 |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 42/966 | 399/17913 | 0e+00 | 0.0006 | 42 |
| GO:0032615 | interleukin-12 production | 12/966 | 55/17913 | 0e+00 | 0.0006 | 12 |
| GO:0009306 | protein secretion | 53/966 | 549/17913 | 0e+00 | 0.0006 | 53 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 51/966 | 522/17913 | 0e+00 | 0.0006 | 51 |
| GO:0009743 | response to carbohydrate | 28/966 | 224/17913 | 0e+00 | 0.0006 | 28 |
| GO:0044766 | multi-organism transport | 14/966 | 73/17913 | 0e+00 | 0.0006 | 14 |
| GO:1902579 | multi-organism localization | 14/966 | 73/17913 | 0e+00 | 0.0006 | 14 |
| GO:0001504 | neurotransmitter uptake | 10/966 | 39/17913 | 0e+00 | 0.0006 | 10 |
| GO:0044257 | cellular protein catabolic process | 60/966 | 648/17913 | 0e+00 | 0.0006 | 60 |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | 24/966 | 178/17913 | 0e+00 | 0.0007 | 24 |
| GO:0071347 | cellular response to interleukin-1 | 22/966 | 156/17913 | 0e+00 | 0.0007 | 22 |
| GO:0044057 | regulation of system process | 56/966 | 594/17913 | 0e+00 | 0.0007 | 56 |
| GO:0006606 | protein import into nucleus | 17/966 | 103/17913 | 0e+00 | 0.0007 | 17 |
| GO:0048524 | positive regulation of viral process | 17/966 | 103/17913 | 0e+00 | 0.0007 | 17 |
| GO:0031347 | regulation of defense response | 76/966 | 885/17913 | 0e+00 | 0.0008 | 76 |
| GO:0002009 | morphogenesis of an epithelium | 51/966 | 527/17913 | 0e+00 | 0.0008 | 51 |
| GO:0015980 | energy derivation by oxidation of organic compounds | 31/966 | 264/17913 | 0e+00 | 0.0008 | 31 |
| GO:0050796 | regulation of insulin secretion | 23/966 | 169/17913 | 0e+00 | 0.0008 | 23 |
| GO:0048024 | regulation of mRNA splicing, via spliceosome | 14/966 | 75/17913 | 0e+00 | 0.0008 | 14 |
| GO:0046677 | response to antibiotic | 36/966 | 328/17913 | 0e+00 | 0.0008 | 36 |
| GO:0075733 | intracellular transport of virus | 12/966 | 57/17913 | 0e+00 | 0.0008 | 12 |
| GO:0002366 | leukocyte activation involved in immune response | 62/966 | 684/17913 | 0e+00 | 0.0008 | 62 |
| GO:0043484 | regulation of RNA splicing | 18/966 | 115/17913 | 0e+00 | 0.0008 | 18 |
| GO:0006281 | DNA repair | 49/966 | 502/17913 | 0e+00 | 0.0009 | 49 |
| GO:0038093 | Fc receptor signaling pathway | 29/966 | 241/17913 | 0e+00 | 0.0009 | 29 |
| GO:0051954 | positive regulation of amine transport | 9/966 | 33/17913 | 0e+00 | 0.0009 | 9 |
| GO:0045666 | positive regulation of neuron differentiation | 38/966 | 355/17913 | 0e+00 | 0.0009 | 38 |
| GO:0050770 | regulation of axonogenesis | 21/966 | 148/17913 | 0e+00 | 0.0009 | 21 |
| GO:2000736 | regulation of stem cell differentiation | 18/966 | 116/17913 | 0e+00 | 0.0009 | 18 |
| GO:0015837 | amine transport | 14/966 | 76/17913 | 0e+00 | 0.0009 | 14 |
| GO:0034622 | cellular protein-containing complex assembly | 80/966 | 952/17913 | 0e+00 | 0.0010 | 80 |
| GO:0002263 | cell activation involved in immune response | 62/966 | 688/17913 | 0e+00 | 0.0010 | 62 |
| GO:0071383 | cellular response to steroid hormone stimulus | 29/966 | 243/17913 | 1e-04 | 0.0010 | 29 |
| GO:2001233 | regulation of apoptotic signaling pathway | 41/966 | 397/17913 | 1e-04 | 0.0010 | 41 |
| GO:0018105 | peptidyl-serine phosphorylation | 28/966 | 231/17913 | 1e-04 | 0.0010 | 28 |
| GO:0006897 | endocytosis | 61/966 | 675/17913 | 1e-04 | 0.0010 | 61 |
| GO:0034605 | cellular response to heat | 18/966 | 117/17913 | 1e-04 | 0.0010 | 18 |
| GO:0030099 | myeloid cell differentiation | 42/966 | 411/17913 | 1e-04 | 0.0010 | 42 |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 17/966 | 107/17913 | 1e-04 | 0.0011 | 17 |
| GO:0006403 | RNA localization | 26/966 | 208/17913 | 1e-04 | 0.0011 | 26 |
| GO:0062012 | regulation of small molecule metabolic process | 44/966 | 439/17913 | 1e-04 | 0.0011 | 44 |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 65/966 | 735/17913 | 1e-04 | 0.0011 | 65 |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity | 30/966 | 257/17913 | 1e-04 | 0.0011 | 30 |
| GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 24/966 | 185/17913 | 1e-04 | 0.0011 | 24 |
| GO:0098660 | inorganic ion transmembrane transport | 64/966 | 722/17913 | 1e-04 | 0.0011 | 64 |
| GO:0051588 | regulation of neurotransmitter transport | 19/966 | 129/17913 | 1e-04 | 0.0011 | 19 |
| GO:0050684 | regulation of mRNA processing | 17/966 | 108/17913 | 1e-04 | 0.0012 | 17 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 49/966 | 510/17913 | 1e-04 | 0.0012 | 49 |
| GO:0043405 | regulation of MAP kinase activity | 35/966 | 322/17913 | 1e-04 | 0.0012 | 35 |
| GO:0032989 | cellular component morphogenesis | 80/966 | 960/17913 | 1e-04 | 0.0012 | 80 |
| GO:0055074 | calcium ion homeostasis | 40/966 | 388/17913 | 1e-04 | 0.0012 | 40 |
| GO:0006874 | cellular calcium ion homeostasis | 39/966 | 375/17913 | 1e-04 | 0.0012 | 39 |
| GO:0043065 | positive regulation of apoptotic process | 59/966 | 652/17913 | 1e-04 | 0.0012 | 59 |
| GO:0035690 | cellular response to drug | 38/966 | 362/17913 | 1e-04 | 0.0012 | 38 |
| GO:1903312 | negative regulation of mRNA metabolic process | 13/966 | 69/17913 | 1e-04 | 0.0013 | 13 |
| GO:0022407 | regulation of cell-cell adhesion | 40/966 | 389/17913 | 1e-04 | 0.0013 | 40 |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 55/966 | 596/17913 | 1e-04 | 0.0013 | 55 |
| GO:0017157 | regulation of exocytosis | 24/966 | 187/17913 | 1e-04 | 0.0013 | 24 |
| GO:0090175 | regulation of establishment of planar polarity | 17/966 | 109/17913 | 1e-04 | 0.0013 | 17 |
| GO:0002064 | epithelial cell development | 25/966 | 199/17913 | 1e-04 | 0.0013 | 25 |
| GO:0006937 | regulation of muscle contraction | 22/966 | 164/17913 | 1e-04 | 0.0013 | 22 |
| GO:0051052 | regulation of DNA metabolic process | 41/966 | 403/17913 | 1e-04 | 0.0013 | 41 |
| GO:0051101 | regulation of DNA binding | 18/966 | 120/17913 | 1e-04 | 0.0013 | 18 |
| GO:0044703 | multi-organism reproductive process | 81/966 | 980/17913 | 1e-04 | 0.0014 | 81 |
| GO:0006402 | mRNA catabolic process | 36/966 | 338/17913 | 1e-04 | 0.0014 | 36 |
| GO:0034284 | response to monosaccharide | 25/966 | 200/17913 | 1e-04 | 0.0014 | 25 |
| GO:0042098 | T cell proliferation | 23/966 | 177/17913 | 1e-04 | 0.0014 | 23 |
| GO:0008361 | regulation of cell size | 21/966 | 154/17913 | 1e-04 | 0.0014 | 21 |
| GO:0019941 | modification-dependent protein catabolic process | 49/966 | 515/17913 | 1e-04 | 0.0014 | 49 |
| GO:0030100 | regulation of endocytosis | 30/966 | 262/17913 | 1e-04 | 0.0014 | 30 |
| GO:0006470 | protein dephosphorylation | 34/966 | 313/17913 | 1e-04 | 0.0014 | 34 |
| GO:0002886 | regulation of myeloid leukocyte mediated immunity | 11/966 | 52/17913 | 1e-04 | 0.0014 | 11 |
| GO:0002573 | myeloid leukocyte differentiation | 25/966 | 201/17913 | 1e-04 | 0.0014 | 25 |
| GO:0007623 | circadian rhythm | 25/966 | 201/17913 | 1e-04 | 0.0014 | 25 |
| GO:0050804 | modulation of chemical synaptic transmission | 40/966 | 393/17913 | 1e-04 | 0.0015 | 40 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 28/966 | 238/17913 | 1e-04 | 0.0015 | 28 |
| GO:0045165 | cell fate commitment | 28/966 | 238/17913 | 1e-04 | 0.0015 | 28 |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 53/966 | 573/17913 | 1e-04 | 0.0015 | 53 |
| GO:0048812 | neuron projection morphogenesis | 52/966 | 559/17913 | 1e-04 | 0.0015 | 52 |
| GO:0010817 | regulation of hormone levels | 48/966 | 503/17913 | 1e-04 | 0.0015 | 48 |
| GO:0003012 | muscle system process | 44/966 | 448/17913 | 1e-04 | 0.0015 | 44 |
| GO:0051656 | establishment of organelle localization | 44/966 | 448/17913 | 1e-04 | 0.0015 | 44 |
| GO:0060560 | developmental growth involved in morphogenesis | 26/966 | 214/17913 | 1e-04 | 0.0015 | 26 |
| GO:0099177 | regulation of trans-synaptic signaling | 40/966 | 394/17913 | 1e-04 | 0.0015 | 40 |
| GO:0071363 | cellular response to growth factor stimulus | 60/966 | 674/17913 | 1e-04 | 0.0015 | 60 |
| GO:0043068 | positive regulation of programmed cell death | 59/966 | 660/17913 | 1e-04 | 0.0016 | 59 |
| GO:0030162 | regulation of proteolysis | 66/966 | 762/17913 | 1e-04 | 0.0016 | 66 |
| GO:0043900 | regulation of multi-organism process | 41/966 | 408/17913 | 1e-04 | 0.0016 | 41 |
| GO:0018209 | peptidyl-serine modification | 29/966 | 252/17913 | 1e-04 | 0.0016 | 29 |
| GO:0007584 | response to nutrient | 26/966 | 215/17913 | 1e-04 | 0.0016 | 26 |
| GO:0032147 | activation of protein kinase activity | 33/966 | 303/17913 | 1e-04 | 0.0016 | 33 |
| GO:0032655 | regulation of interleukin-12 production | 11/966 | 53/17913 | 1e-04 | 0.0016 | 11 |
| GO:0010976 | positive regulation of neuron projection development | 30/966 | 265/17913 | 1e-04 | 0.0016 | 30 |
| GO:0001736 | establishment of planar polarity | 18/966 | 123/17913 | 1e-04 | 0.0017 | 18 |
| GO:0007164 | establishment of tissue polarity | 18/966 | 123/17913 | 1e-04 | 0.0017 | 18 |
| GO:0015850 | organic hydroxy compound transport | 27/966 | 228/17913 | 1e-04 | 0.0017 | 27 |
| GO:0051650 | establishment of vesicle localization | 29/966 | 253/17913 | 1e-04 | 0.0017 | 29 |
| GO:0048858 | cell projection morphogenesis | 53/966 | 577/17913 | 1e-04 | 0.0017 | 53 |
| GO:0002888 | positive regulation of myeloid leukocyte mediated immunity | 8/966 | 29/17913 | 1e-04 | 0.0017 | 8 |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 46/966 | 479/17913 | 1e-04 | 0.0017 | 46 |
| GO:0051651 | maintenance of location in cell | 13/966 | 72/17913 | 1e-04 | 0.0017 | 13 |
| GO:0007610 | behavior | 53/966 | 578/17913 | 1e-04 | 0.0018 | 53 |
| GO:0045921 | positive regulation of exocytosis | 14/966 | 82/17913 | 1e-04 | 0.0018 | 14 |
| GO:0051817 | modification of morphology or physiology of other organism involved in symbiotic interaction | 17/966 | 113/17913 | 1e-04 | 0.0018 | 17 |
| GO:0050900 | leukocyte migration | 45/966 | 467/17913 | 1e-04 | 0.0019 | 45 |
| GO:0045088 | regulation of innate immune response | 43/966 | 440/17913 | 1e-04 | 0.0019 | 43 |
| GO:0010942 | positive regulation of cell death | 62/966 | 710/17913 | 1e-04 | 0.0019 | 62 |
| GO:0060249 | anatomical structure homeostasis | 41/966 | 413/17913 | 1e-04 | 0.0019 | 41 |
| GO:0032990 | cell part morphogenesis | 54/966 | 595/17913 | 1e-04 | 0.0019 | 54 |
| GO:0046887 | positive regulation of hormone secretion | 18/966 | 125/17913 | 1e-04 | 0.0020 | 18 |
| GO:0019932 | second-messenger-mediated signaling | 37/966 | 360/17913 | 1e-04 | 0.0020 | 37 |
| GO:0070997 | neuron death | 36/966 | 347/17913 | 1e-04 | 0.0020 | 36 |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 42/966 | 428/17913 | 1e-04 | 0.0020 | 42 |
| GO:0045926 | negative regulation of growth | 28/966 | 244/17913 | 1e-04 | 0.0021 | 28 |
| GO:1902600 | proton transmembrane transport | 20/966 | 148/17913 | 1e-04 | 0.0021 | 20 |
| GO:0098586 | cellular response to virus | 11/966 | 55/17913 | 1e-04 | 0.0022 | 11 |
| GO:0051272 | positive regulation of cellular component movement | 51/966 | 555/17913 | 1e-04 | 0.0022 | 51 |
| GO:0009790 | embryo development | 79/966 | 968/17913 | 1e-04 | 0.0022 | 79 |
| GO:0071902 | positive regulation of protein serine/threonine kinase activity | 34/966 | 322/17913 | 1e-04 | 0.0022 | 34 |
| GO:0002521 | leukocyte differentiation | 46/966 | 485/17913 | 1e-04 | 0.0022 | 46 |
| GO:0016572 | histone phosphorylation | 9/966 | 38/17913 | 1e-04 | 0.0022 | 9 |
| GO:0071214 | cellular response to abiotic stimulus | 33/966 | 310/17913 | 2e-04 | 0.0023 | 33 |
| GO:0104004 | cellular response to environmental stimulus | 33/966 | 310/17913 | 2e-04 | 0.0023 | 33 |
| GO:0098662 | inorganic cation transmembrane transport | 57/966 | 643/17913 | 2e-04 | 0.0023 | 57 |
| GO:0007569 | cell aging | 17/966 | 116/17913 | 2e-04 | 0.0023 | 17 |
| GO:0030155 | regulation of cell adhesion | 58/966 | 659/17913 | 2e-04 | 0.0024 | 58 |
| GO:0002758 | innate immune response-activating signal transduction | 32/966 | 298/17913 | 2e-04 | 0.0024 | 32 |
| GO:0045137 | development of primary sexual characteristics | 26/966 | 223/17913 | 2e-04 | 0.0026 | 26 |
| GO:0018279 | protein N-linked glycosylation via asparagine | 8/966 | 31/17913 | 2e-04 | 0.0026 | 8 |
| GO:0015844 | monoamine transport | 12/966 | 66/17913 | 2e-04 | 0.0027 | 12 |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | 53/966 | 590/17913 | 2e-04 | 0.0027 | 53 |
| GO:0032392 | DNA geometric change | 14/966 | 86/17913 | 2e-04 | 0.0028 | 14 |
| GO:0010506 | regulation of autophagy | 33/966 | 314/17913 | 2e-04 | 0.0028 | 33 |
| GO:0060047 | heart contraction | 30/966 | 275/17913 | 2e-04 | 0.0028 | 30 |
| GO:0032890 | regulation of organic acid transport | 11/966 | 57/17913 | 2e-04 | 0.0029 | 11 |
| GO:0033119 | negative regulation of RNA splicing | 7/966 | 24/17913 | 2e-04 | 0.0029 | 7 |
| GO:0043406 | positive regulation of MAP kinase activity | 28/966 | 250/17913 | 2e-04 | 0.0029 | 28 |
| GO:0001889 | liver development | 18/966 | 130/17913 | 2e-04 | 0.0030 | 18 |
| GO:0046683 | response to organophosphorus | 18/966 | 130/17913 | 2e-04 | 0.0030 | 18 |
| GO:0090257 | regulation of muscle system process | 28/966 | 251/17913 | 2e-04 | 0.0031 | 28 |
| GO:0044772 | mitotic cell cycle phase transition | 51/966 | 565/17913 | 2e-04 | 0.0031 | 51 |
| GO:0048598 | embryonic morphogenesis | 51/966 | 565/17913 | 2e-04 | 0.0031 | 51 |
| GO:0042987 | amyloid precursor protein catabolic process | 9/966 | 40/17913 | 2e-04 | 0.0032 | 9 |
| GO:0097193 | intrinsic apoptotic signaling pathway | 30/966 | 277/17913 | 2e-04 | 0.0032 | 30 |
| GO:0001678 | cellular glucose homeostasis | 19/966 | 142/17913 | 2e-04 | 0.0032 | 19 |
| GO:0018196 | peptidyl-asparagine modification | 8/966 | 32/17913 | 2e-04 | 0.0032 | 8 |
| GO:1903047 | mitotic cell cycle process | 68/966 | 816/17913 | 2e-04 | 0.0032 | 68 |
| GO:0034762 | regulation of transmembrane transport | 49/966 | 538/17913 | 2e-04 | 0.0033 | 49 |
| GO:1902749 | regulation of cell cycle G2/M phase transition | 24/966 | 202/17913 | 2e-04 | 0.0033 | 24 |
| GO:0007187 | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 22/966 | 178/17913 | 2e-04 | 0.0034 | 22 |
| GO:0007369 | gastrulation | 22/966 | 178/17913 | 2e-04 | 0.0034 | 22 |
| GO:0039535 | regulation of RIG-I signaling pathway | 6/966 | 18/17913 | 3e-04 | 0.0035 | 6 |
| GO:0046641 | positive regulation of alpha-beta T cell proliferation | 6/966 | 18/17913 | 3e-04 | 0.0035 | 6 |
| GO:0038061 | NIK/NF-kappaB signaling | 22/966 | 179/17913 | 3e-04 | 0.0036 | 22 |
| GO:0051236 | establishment of RNA localization | 22/966 | 179/17913 | 3e-04 | 0.0036 | 22 |
| GO:0002218 | activation of innate immune response | 33/966 | 319/17913 | 3e-04 | 0.0036 | 33 |
| GO:0048872 | homeostasis of number of cells | 27/966 | 241/17913 | 3e-04 | 0.0036 | 27 |
| GO:0015991 | ATP hydrolysis coupled proton transport | 7/966 | 25/17913 | 3e-04 | 0.0036 | 7 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 35/966 | 346/17913 | 3e-04 | 0.0036 | 35 |
| GO:0043062 | extracellular structure organization | 38/966 | 387/17913 | 3e-04 | 0.0037 | 38 |
| GO:0050434 | positive regulation of viral transcription | 9/966 | 41/17913 | 3e-04 | 0.0037 | 9 |
| GO:0042391 | regulation of membrane potential | 37/966 | 374/17913 | 3e-04 | 0.0038 | 37 |
| GO:0061008 | hepaticobiliary system development | 18/966 | 133/17913 | 3e-04 | 0.0038 | 18 |
| GO:0008406 | gonad development | 25/966 | 217/17913 | 3e-04 | 0.0038 | 25 |
| GO:0032892 | positive regulation of organic acid transport | 8/966 | 33/17913 | 3e-04 | 0.0039 | 8 |
| GO:0006353 | DNA-templated transcription, termination | 12/966 | 69/17913 | 3e-04 | 0.0039 | 12 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 12/966 | 69/17913 | 3e-04 | 0.0039 | 12 |
| GO:0046822 | regulation of nucleocytoplasmic transport | 15/966 | 100/17913 | 3e-04 | 0.0039 | 15 |
| GO:0006405 | RNA export from nucleus | 17/966 | 122/17913 | 3e-04 | 0.0039 | 17 |
| GO:0010975 | regulation of neuron projection development | 43/966 | 458/17913 | 3e-04 | 0.0039 | 43 |
| GO:0070848 | response to growth factor | 60/966 | 704/17913 | 3e-04 | 0.0040 | 60 |
| GO:0031346 | positive regulation of cell projection organization | 36/966 | 362/17913 | 3e-04 | 0.0040 | 36 |
| GO:0010564 | regulation of cell cycle process | 64/966 | 764/17913 | 3e-04 | 0.0040 | 64 |
| GO:0043401 | steroid hormone mediated signaling pathway | 22/966 | 181/17913 | 3e-04 | 0.0040 | 22 |
| GO:0051099 | positive regulation of binding | 22/966 | 181/17913 | 3e-04 | 0.0040 | 22 |
| GO:0061387 | regulation of extent of cell growth | 14/966 | 90/17913 | 3e-04 | 0.0041 | 14 |
| GO:0018212 | peptidyl-tyrosine modification | 35/966 | 349/17913 | 3e-04 | 0.0041 | 35 |
| GO:0010469 | regulation of signaling receptor activity | 52/966 | 588/17913 | 3e-04 | 0.0041 | 52 |
| GO:0007599 | hemostasis | 34/966 | 336/17913 | 3e-04 | 0.0042 | 34 |
| GO:0032479 | regulation of type I interferon production | 17/966 | 123/17913 | 3e-04 | 0.0042 | 17 |
| GO:0044839 | cell cycle G2/M phase transition | 28/966 | 257/17913 | 3e-04 | 0.0042 | 28 |
| GO:0009410 | response to xenobiotic stimulus | 29/966 | 270/17913 | 3e-04 | 0.0042 | 29 |
| GO:0051648 | vesicle localization | 29/966 | 270/17913 | 3e-04 | 0.0042 | 29 |
| GO:0048675 | axon extension | 15/966 | 101/17913 | 3e-04 | 0.0042 | 15 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 20/966 | 158/17913 | 3e-04 | 0.0043 | 20 |
| GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 26/966 | 232/17913 | 3e-04 | 0.0043 | 26 |
| GO:0050817 | coagulation | 34/966 | 337/17913 | 3e-04 | 0.0043 | 34 |
| GO:0003015 | heart process | 30/966 | 284/17913 | 3e-04 | 0.0044 | 30 |
| GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient | 7/966 | 26/17913 | 3e-04 | 0.0044 | 7 |
| GO:0009746 | response to hexose | 23/966 | 195/17913 | 4e-04 | 0.0044 | 23 |
| GO:0010959 | regulation of metal ion transport | 36/966 | 365/17913 | 4e-04 | 0.0045 | 36 |
| GO:0042177 | negative regulation of protein catabolic process | 17/966 | 124/17913 | 4e-04 | 0.0045 | 17 |
| GO:0048025 | negative regulation of mRNA splicing, via spliceosome | 6/966 | 19/17913 | 4e-04 | 0.0045 | 6 |
| GO:1990182 | exosomal secretion | 6/966 | 19/17913 | 4e-04 | 0.0045 | 6 |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 16/966 | 113/17913 | 4e-04 | 0.0046 | 16 |
| GO:0048645 | animal organ formation | 11/966 | 61/17913 | 4e-04 | 0.0046 | 11 |
| GO:0015931 | nucleobase-containing compound transport | 25/966 | 221/17913 | 4e-04 | 0.0047 | 25 |
| GO:0007346 | regulation of mitotic cell cycle | 54/966 | 622/17913 | 4e-04 | 0.0047 | 54 |
| GO:1901987 | regulation of cell cycle phase transition | 43/966 | 464/17913 | 4e-04 | 0.0048 | 43 |
| GO:0051235 | maintenance of location | 30/966 | 286/17913 | 4e-04 | 0.0048 | 30 |
| GO:0032606 | type I interferon production | 17/966 | 125/17913 | 4e-04 | 0.0048 | 17 |
| GO:0042060 | wound healing | 49/966 | 550/17913 | 4e-04 | 0.0048 | 49 |
| GO:1904646 | cellular response to amyloid-beta | 9/966 | 43/17913 | 4e-04 | 0.0049 | 9 |
| GO:0032091 | negative regulation of protein binding | 15/966 | 103/17913 | 4e-04 | 0.0050 | 15 |
| GO:0044770 | cell cycle phase transition | 53/966 | 609/17913 | 4e-04 | 0.0050 | 53 |
| GO:0043254 | regulation of protein complex assembly | 39/966 | 409/17913 | 4e-04 | 0.0050 | 39 |
| GO:0042176 | regulation of protein catabolic process | 35/966 | 354/17913 | 4e-04 | 0.0050 | 35 |
| GO:0046034 | ATP metabolic process | 30/966 | 287/17913 | 4e-04 | 0.0050 | 30 |
| GO:1901991 | negative regulation of mitotic cell cycle phase transition | 26/966 | 235/17913 | 4e-04 | 0.0050 | 26 |
| GO:0006970 | response to osmotic stress | 13/966 | 82/17913 | 4e-04 | 0.0051 | 13 |
| GO:0046777 | protein autophosphorylation | 24/966 | 210/17913 | 4e-04 | 0.0051 | 24 |
| GO:0042129 | regulation of T cell proliferation | 19/966 | 149/17913 | 4e-04 | 0.0051 | 19 |
| GO:0016049 | cell growth | 43/966 | 466/17913 | 4e-04 | 0.0051 | 43 |
| GO:0050772 | positive regulation of axonogenesis | 12/966 | 72/17913 | 4e-04 | 0.0052 | 12 |
| GO:0051591 | response to cAMP | 14/966 | 93/17913 | 4e-04 | 0.0053 | 14 |
| GO:0050686 | negative regulation of mRNA processing | 7/966 | 27/17913 | 4e-04 | 0.0053 | 7 |
| GO:0099131 | ATP hydrolysis coupled ion transmembrane transport | 7/966 | 27/17913 | 4e-04 | 0.0053 | 7 |
| GO:0098655 | cation transmembrane transport | 61/966 | 730/17913 | 4e-04 | 0.0053 | 61 |
| GO:0099003 | vesicle-mediated transport in synapse | 21/966 | 174/17913 | 5e-04 | 0.0055 | 21 |
| GO:0070838 | divalent metal ion transport | 42/966 | 454/17913 | 5e-04 | 0.0056 | 42 |
| GO:0034764 | positive regulation of transmembrane transport | 23/966 | 199/17913 | 5e-04 | 0.0056 | 23 |
| GO:0050670 | regulation of lymphocyte proliferation | 23/966 | 199/17913 | 5e-04 | 0.0056 | 23 |
| GO:2000147 | positive regulation of cell motility | 48/966 | 540/17913 | 5e-04 | 0.0056 | 48 |
| GO:0034383 | low-density lipoprotein particle clearance | 9/966 | 44/17913 | 5e-04 | 0.0056 | 9 |
| GO:0039529 | RIG-I signaling pathway | 6/966 | 20/17913 | 5e-04 | 0.0057 | 6 |
| GO:0042053 | regulation of dopamine metabolic process | 6/966 | 20/17913 | 5e-04 | 0.0057 | 6 |
| GO:0042069 | regulation of catecholamine metabolic process | 6/966 | 20/17913 | 5e-04 | 0.0057 | 6 |
| GO:0097734 | extracellular exosome biogenesis | 6/966 | 20/17913 | 5e-04 | 0.0057 | 6 |
| GO:0002220 | innate immune response activating cell surface receptor signaling pathway | 16/966 | 116/17913 | 5e-04 | 0.0057 | 16 |
| GO:0071426 | ribonucleoprotein complex export from nucleus | 16/966 | 116/17913 | 5e-04 | 0.0057 | 16 |
| GO:0051129 | negative regulation of cellular component organization | 57/966 | 673/17913 | 5e-04 | 0.0057 | 57 |
| GO:0001738 | morphogenesis of a polarized epithelium | 18/966 | 139/17913 | 5e-04 | 0.0057 | 18 |
| GO:0071322 | cellular response to carbohydrate stimulus | 18/966 | 139/17913 | 5e-04 | 0.0057 | 18 |
| GO:0002697 | regulation of immune effector process | 41/966 | 441/17913 | 5e-04 | 0.0057 | 41 |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 19/966 | 151/17913 | 5e-04 | 0.0057 | 19 |
| GO:0006611 | protein export from nucleus | 20/966 | 163/17913 | 5e-04 | 0.0057 | 20 |
| GO:0051402 | neuron apoptotic process | 26/966 | 238/17913 | 5e-04 | 0.0057 | 26 |
| GO:0072331 | signal transduction by p53 class mediator | 28/966 | 264/17913 | 5e-04 | 0.0057 | 28 |
| GO:0032944 | regulation of mononuclear cell proliferation | 23/966 | 200/17913 | 5e-04 | 0.0058 | 23 |
| GO:0007596 | blood coagulation | 33/966 | 331/17913 | 5e-04 | 0.0058 | 33 |
| GO:0050708 | regulation of protein secretion | 42/966 | 456/17913 | 5e-04 | 0.0058 | 42 |
| GO:0046649 | lymphocyte activation | 54/966 | 630/17913 | 5e-04 | 0.0059 | 54 |
| GO:0008286 | insulin receptor signaling pathway | 17/966 | 128/17913 | 5e-04 | 0.0059 | 17 |
| GO:0006914 | autophagy | 43/966 | 471/17913 | 5e-04 | 0.0060 | 43 |
| GO:0061919 | process utilizing autophagic mechanism | 43/966 | 471/17913 | 5e-04 | 0.0060 | 43 |
| GO:0050657 | nucleic acid transport | 21/966 | 176/17913 | 5e-04 | 0.0060 | 21 |
| GO:0050658 | RNA transport | 21/966 | 176/17913 | 5e-04 | 0.0060 | 21 |
| GO:0051168 | nuclear export | 21/966 | 176/17913 | 5e-04 | 0.0060 | 21 |
| GO:0045089 | positive regulation of innate immune response | 36/966 | 373/17913 | 5e-04 | 0.0060 | 36 |
| GO:0017038 | protein import | 18/966 | 140/17913 | 5e-04 | 0.0060 | 18 |
| GO:0042110 | T cell activation | 41/966 | 443/17913 | 5e-04 | 0.0060 | 41 |
| GO:0071166 | ribonucleoprotein complex localization | 16/966 | 117/17913 | 5e-04 | 0.0060 | 16 |
| GO:1900180 | regulation of protein localization to nucleus | 16/966 | 117/17913 | 5e-04 | 0.0060 | 16 |
| GO:2001020 | regulation of response to DNA damage stimulus | 23/966 | 201/17913 | 5e-04 | 0.0060 | 23 |
| GO:1904645 | response to amyloid-beta | 10/966 | 54/17913 | 5e-04 | 0.0060 | 10 |
| GO:0006354 | DNA-templated transcription, elongation | 15/966 | 106/17913 | 6e-04 | 0.0061 | 15 |
| GO:0043200 | response to amino acid | 15/966 | 106/17913 | 6e-04 | 0.0061 | 15 |
| GO:0070663 | regulation of leukocyte proliferation | 24/966 | 214/17913 | 6e-04 | 0.0061 | 24 |
| GO:0016311 | dephosphorylation | 42/966 | 458/17913 | 6e-04 | 0.0061 | 42 |
| GO:0072511 | divalent inorganic cation transport | 42/966 | 458/17913 | 6e-04 | 0.0061 | 42 |
| GO:0030104 | water homeostasis | 12/966 | 74/17913 | 6e-04 | 0.0061 | 12 |
| GO:0032481 | positive regulation of type I interferon production | 12/966 | 74/17913 | 6e-04 | 0.0061 | 12 |
| GO:0090662 | ATP hydrolysis coupled transmembrane transport | 7/966 | 28/17913 | 6e-04 | 0.0062 | 7 |
| GO:0010463 | mesenchymal cell proliferation | 9/966 | 45/17913 | 6e-04 | 0.0062 | 9 |
| GO:0046782 | regulation of viral transcription | 11/966 | 64/17913 | 6e-04 | 0.0062 | 11 |
| GO:2000145 | regulation of cell motility | 76/966 | 966/17913 | 6e-04 | 0.0062 | 76 |
| GO:0009749 | response to glucose | 22/966 | 190/17913 | 6e-04 | 0.0065 | 22 |
| GO:0022037 | metencephalon development | 15/966 | 107/17913 | 6e-04 | 0.0066 | 15 |
| GO:0039531 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | 6/966 | 21/17913 | 7e-04 | 0.0070 | 6 |
| GO:0003009 | skeletal muscle contraction | 8/966 | 37/17913 | 7e-04 | 0.0071 | 8 |
| GO:0051590 | positive regulation of neurotransmitter transport | 8/966 | 37/17913 | 7e-04 | 0.0071 | 8 |
| GO:0050792 | regulation of viral process | 23/966 | 204/17913 | 7e-04 | 0.0072 | 23 |
| GO:1901796 | regulation of signal transduction by p53 class mediator | 21/966 | 179/17913 | 7e-04 | 0.0072 | 21 |
| GO:0071326 | cellular response to monosaccharide stimulus | 17/966 | 131/17913 | 7e-04 | 0.0073 | 17 |
| GO:0061136 | regulation of proteasomal protein catabolic process | 20/966 | 167/17913 | 7e-04 | 0.0073 | 20 |
| GO:0009314 | response to radiation | 40/966 | 435/17913 | 7e-04 | 0.0076 | 40 |
| GO:0034205 | amyloid-beta formation | 7/966 | 29/17913 | 7e-04 | 0.0076 | 7 |
| GO:0070661 | leukocyte proliferation | 28/966 | 270/17913 | 7e-04 | 0.0076 | 28 |
| GO:0032508 | DNA duplex unwinding | 12/966 | 76/17913 | 7e-04 | 0.0076 | 12 |
| GO:0019058 | viral life cycle | 32/966 | 324/17913 | 7e-04 | 0.0076 | 32 |
| GO:0046651 | lymphocyte proliferation | 26/966 | 244/17913 | 7e-04 | 0.0077 | 26 |
| GO:0051924 | regulation of calcium ion transport | 26/966 | 244/17913 | 7e-04 | 0.0077 | 26 |
| GO:0033044 | regulation of chromosome organization | 31/966 | 311/17913 | 7e-04 | 0.0078 | 31 |
| GO:0050727 | regulation of inflammatory response | 43/966 | 479/17913 | 7e-04 | 0.0078 | 43 |
| GO:0021549 | cerebellum development | 14/966 | 98/17913 | 8e-04 | 0.0080 | 14 |
| GO:0048638 | regulation of developmental growth | 32/966 | 325/17913 | 8e-04 | 0.0080 | 32 |
| GO:1903827 | regulation of cellular protein localization | 45/966 | 509/17913 | 8e-04 | 0.0082 | 45 |
| GO:0008217 | regulation of blood pressure | 20/966 | 169/17913 | 8e-04 | 0.0083 | 20 |
| GO:0060401 | cytosolic calcium ion transport | 19/966 | 157/17913 | 8e-04 | 0.0084 | 19 |
| GO:0002262 | myeloid cell homeostasis | 18/966 | 145/17913 | 8e-04 | 0.0084 | 18 |
| GO:0014074 | response to purine-containing compound | 18/966 | 145/17913 | 8e-04 | 0.0084 | 18 |
| GO:0060402 | calcium ion transport into cytosol | 18/966 | 145/17913 | 8e-04 | 0.0084 | 18 |
| GO:0032943 | mononuclear cell proliferation | 26/966 | 246/17913 | 8e-04 | 0.0085 | 26 |
| GO:0001558 | regulation of cell growth | 37/966 | 396/17913 | 8e-04 | 0.0085 | 37 |
| GO:1903708 | positive regulation of hemopoiesis | 21/966 | 182/17913 | 8e-04 | 0.0086 | 21 |
| GO:0019430 | removal of superoxide radicals | 6/966 | 22/17913 | 9e-04 | 0.0087 | 6 |
| GO:0043302 | positive regulation of leukocyte degranulation | 6/966 | 22/17913 | 9e-04 | 0.0087 | 6 |
| GO:0140112 | extracellular vesicle biogenesis | 6/966 | 22/17913 | 9e-04 | 0.0087 | 6 |
| GO:0097529 | myeloid leukocyte migration | 20/966 | 170/17913 | 9e-04 | 0.0087 | 20 |
| GO:0055067 | monovalent inorganic cation homeostasis | 16/966 | 122/17913 | 9e-04 | 0.0087 | 16 |
| GO:0017014 | protein nitrosylation | 5/966 | 15/17913 | 9e-04 | 0.0087 | 5 |
| GO:0018119 | peptidyl-cysteine S-nitrosylation | 5/966 | 15/17913 | 9e-04 | 0.0087 | 5 |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 27/966 | 260/17913 | 9e-04 | 0.0088 | 27 |
| GO:0040017 | positive regulation of locomotion | 49/966 | 570/17913 | 9e-04 | 0.0088 | 49 |
| GO:0000278 | mitotic cell cycle | 73/966 | 934/17913 | 9e-04 | 0.0089 | 73 |
| GO:0031349 | positive regulation of defense response | 45/966 | 512/17913 | 9e-04 | 0.0089 | 45 |
| GO:0051028 | mRNA transport | 18/966 | 146/17913 | 9e-04 | 0.0089 | 18 |
| GO:0016055 | Wnt signaling pathway | 44/966 | 498/17913 | 9e-04 | 0.0091 | 44 |
| GO:0052547 | regulation of peptidase activity | 37/966 | 398/17913 | 9e-04 | 0.0091 | 37 |
| GO:0032760 | positive regulation of tumor necrosis factor production | 12/966 | 78/17913 | 9e-04 | 0.0091 | 12 |
| GO:0050821 | protein stabilization | 20/966 | 171/17913 | 9e-04 | 0.0092 | 20 |
| GO:0000209 | protein polyubiquitination | 29/966 | 288/17913 | 9e-04 | 0.0092 | 29 |
| GO:0032648 | regulation of interferon-beta production | 9/966 | 48/17913 | 9e-04 | 0.0092 | 9 |
| GO:0043392 | negative regulation of DNA binding | 9/966 | 48/17913 | 9e-04 | 0.0092 | 9 |
| GO:0048259 | regulation of receptor-mediated endocytosis | 14/966 | 100/17913 | 9e-04 | 0.0092 | 14 |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 14/966 | 100/17913 | 9e-04 | 0.0092 | 14 |
| GO:0042775 | mitochondrial ATP synthesis coupled electron transport | 13/966 | 89/17913 | 9e-04 | 0.0093 | 13 |
| GO:0035967 | cellular response to topologically incorrect protein | 17/966 | 135/17913 | 1e-03 | 0.0095 | 17 |
| GO:0000187 | activation of MAPK activity | 18/966 | 147/17913 | 1e-03 | 0.0095 | 18 |
| GO:0198738 | cell-cell signaling by wnt | 44/966 | 500/17913 | 1e-03 | 0.0096 | 44 |
| GO:0070371 | ERK1 and ERK2 cascade | 29/966 | 289/17913 | 1e-03 | 0.0096 | 29 |
| GO:0008016 | regulation of heart contraction | 26/966 | 249/17913 | 1e-03 | 0.0097 | 26 |
| GO:0007411 | axon guidance | 23/966 | 210/17913 | 1e-03 | 0.0097 | 23 |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 24/966 | 223/17913 | 1e-03 | 0.0098 | 24 |
| GO:0009167 | purine ribonucleoside monophosphate metabolic process | 31/966 | 317/17913 | 1e-03 | 0.0100 | 31 |
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0010243 | response to organonitrogen compound | 57/507 | 932/17913 | 0e+00 | 0.0001 | 57 |
| GO:0033238 | regulation of cellular amine metabolic process | 14/507 | 80/17913 | 0e+00 | 0.0001 | 14 |
| GO:0044106 | cellular amine metabolic process | 17/507 | 121/17913 | 0e+00 | 0.0001 | 17 |
| GO:0006521 | regulation of cellular amino acid metabolic process | 12/507 | 61/17913 | 0e+00 | 0.0001 | 12 |
| GO:0009308 | amine metabolic process | 17/507 | 128/17913 | 0e+00 | 0.0001 | 17 |
| GO:0006457 | protein folding | 20/507 | 176/17913 | 0e+00 | 0.0001 | 20 |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 16/507 | 115/17913 | 0e+00 | 0.0001 | 16 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 13/507 | 77/17913 | 0e+00 | 0.0001 | 13 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 28/507 | 328/17913 | 0e+00 | 0.0001 | 28 |
| GO:0016071 | mRNA metabolic process | 50/507 | 815/17913 | 0e+00 | 0.0001 | 50 |
| GO:0031145 | anaphase-promoting complex-dependent catabolic process | 13/507 | 81/17913 | 0e+00 | 0.0002 | 13 |
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 15/507 | 109/17913 | 0e+00 | 0.0002 | 15 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 14/507 | 95/17913 | 0e+00 | 0.0002 | 14 |
| GO:1901699 | cellular response to nitrogen compound | 41/507 | 620/17913 | 0e+00 | 0.0002 | 41 |
| GO:0019725 | cellular homeostasis | 49/507 | 814/17913 | 0e+00 | 0.0002 | 49 |
| GO:0060218 | hematopoietic stem cell differentiation | 13/507 | 83/17913 | 0e+00 | 0.0002 | 13 |
| GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 13/507 | 85/17913 | 0e+00 | 0.0002 | 13 |
| GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 13/507 | 85/17913 | 0e+00 | 0.0002 | 13 |
| GO:1902036 | regulation of hematopoietic stem cell differentiation | 12/507 | 72/17913 | 0e+00 | 0.0002 | 12 |
| GO:0035567 | non-canonical Wnt signaling pathway | 17/507 | 145/17913 | 0e+00 | 0.0002 | 17 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 36/507 | 522/17913 | 0e+00 | 0.0002 | 36 |
| GO:0070646 | protein modification by small protein removal | 24/507 | 273/17913 | 0e+00 | 0.0002 | 24 |
| GO:1903311 | regulation of mRNA metabolic process | 24/507 | 275/17913 | 0e+00 | 0.0002 | 24 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 35/507 | 510/17913 | 0e+00 | 0.0003 | 35 |
| GO:0051050 | positive regulation of transport | 53/507 | 942/17913 | 0e+00 | 0.0003 | 53 |
| GO:0016579 | protein deubiquitination | 23/507 | 260/17913 | 0e+00 | 0.0003 | 23 |
| GO:0010498 | proteasomal protein catabolic process | 29/507 | 382/17913 | 0e+00 | 0.0003 | 29 |
| GO:0071417 | cellular response to organonitrogen compound | 37/507 | 559/17913 | 0e+00 | 0.0003 | 37 |
| GO:0019941 | modification-dependent protein catabolic process | 35/507 | 515/17913 | 0e+00 | 0.0003 | 35 |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 14/507 | 107/17913 | 0e+00 | 0.0003 | 14 |
| GO:0006520 | cellular amino acid metabolic process | 27/507 | 347/17913 | 0e+00 | 0.0004 | 27 |
| GO:0090175 | regulation of establishment of planar polarity | 14/507 | 109/17913 | 0e+00 | 0.0004 | 14 |
| GO:0062012 | regulation of small molecule metabolic process | 31/507 | 439/17913 | 0e+00 | 0.0005 | 31 |
| GO:1902750 | negative regulation of cell cycle G2/M phase transition | 13/507 | 97/17913 | 0e+00 | 0.0005 | 13 |
| GO:0044257 | cellular protein catabolic process | 40/507 | 648/17913 | 0e+00 | 0.0005 | 40 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 11/507 | 69/17913 | 0e+00 | 0.0005 | 11 |
| GO:0009725 | response to hormone | 51/507 | 920/17913 | 0e+00 | 0.0005 | 51 |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 14/507 | 113/17913 | 0e+00 | 0.0005 | 14 |
| GO:0090276 | regulation of peptide hormone secretion | 19/507 | 199/17913 | 0e+00 | 0.0005 | 19 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 21/507 | 238/17913 | 0e+00 | 0.0005 | 21 |
| GO:0014070 | response to organic cyclic compound | 49/507 | 879/17913 | 0e+00 | 0.0006 | 49 |
| GO:0002220 | innate immune response activating cell surface receptor signaling pathway | 14/507 | 116/17913 | 0e+00 | 0.0006 | 14 |
| GO:2000736 | regulation of stem cell differentiation | 14/507 | 116/17913 | 0e+00 | 0.0006 | 14 |
| GO:0030072 | peptide hormone secretion | 21/507 | 241/17913 | 0e+00 | 0.0006 | 21 |
| GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 18/507 | 185/17913 | 0e+00 | 0.0006 | 18 |
| GO:0006397 | mRNA processing | 33/507 | 499/17913 | 0e+00 | 0.0006 | 33 |
| GO:0008015 | blood circulation | 34/507 | 523/17913 | 0e+00 | 0.0006 | 34 |
| GO:0038095 | Fc-epsilon receptor signaling pathway | 17/507 | 169/17913 | 0e+00 | 0.0006 | 17 |
| GO:0023061 | signal release | 30/507 | 433/17913 | 0e+00 | 0.0006 | 30 |
| GO:0030104 | water homeostasis | 11/507 | 74/17913 | 0e+00 | 0.0007 | 11 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 11/507 | 75/17913 | 0e+00 | 0.0008 | 11 |
| GO:0003013 | circulatory system process | 34/507 | 532/17913 | 0e+00 | 0.0008 | 34 |
| GO:0071347 | cellular response to interleukin-1 | 16/507 | 156/17913 | 0e+00 | 0.0008 | 16 |
| GO:0001736 | establishment of planar polarity | 14/507 | 123/17913 | 0e+00 | 0.0009 | 14 |
| GO:0007164 | establishment of tissue polarity | 14/507 | 123/17913 | 0e+00 | 0.0009 | 14 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 11/507 | 78/17913 | 0e+00 | 0.0010 | 11 |
| GO:0046883 | regulation of hormone secretion | 21/507 | 254/17913 | 0e+00 | 0.0010 | 21 |
| GO:0002520 | immune system development | 50/507 | 938/17913 | 0e+00 | 0.0011 | 50 |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | 36/507 | 590/17913 | 0e+00 | 0.0011 | 36 |
| GO:0048534 | hematopoietic or lymphoid organ development | 48/507 | 890/17913 | 0e+00 | 0.0011 | 48 |
| GO:0044839 | cell cycle G2/M phase transition | 21/507 | 257/17913 | 0e+00 | 0.0011 | 21 |
| GO:0015844 | monoamine transport | 10/507 | 66/17913 | 0e+00 | 0.0012 | 10 |
| GO:0050878 | regulation of body fluid levels | 32/507 | 499/17913 | 0e+00 | 0.0012 | 32 |
| GO:1905330 | regulation of morphogenesis of an epithelium | 17/507 | 181/17913 | 0e+00 | 0.0012 | 17 |
| GO:0017144 | drug metabolic process | 44/507 | 792/17913 | 0e+00 | 0.0012 | 44 |
| GO:0036293 | response to decreased oxygen levels | 26/507 | 365/17913 | 0e+00 | 0.0012 | 26 |
| GO:0046879 | hormone secretion | 23/507 | 301/17913 | 0e+00 | 0.0012 | 23 |
| GO:0030097 | hemopoiesis | 46/507 | 847/17913 | 0e+00 | 0.0013 | 46 |
| GO:0070482 | response to oxygen levels | 27/507 | 389/17913 | 0e+00 | 0.0013 | 27 |
| GO:0038093 | Fc receptor signaling pathway | 20/507 | 241/17913 | 0e+00 | 0.0013 | 20 |
| GO:1902749 | regulation of cell cycle G2/M phase transition | 18/507 | 202/17913 | 0e+00 | 0.0013 | 18 |
| GO:0018279 | protein N-linked glycosylation via asparagine | 7/507 | 31/17913 | 0e+00 | 0.0014 | 7 |
| GO:0043270 | positive regulation of ion transport | 21/507 | 266/17913 | 0e+00 | 0.0016 | 21 |
| GO:0048511 | rhythmic process | 22/507 | 287/17913 | 0e+00 | 0.0016 | 22 |
| GO:0018196 | peptidyl-asparagine modification | 7/507 | 32/17913 | 0e+00 | 0.0016 | 7 |
| GO:0048002 | antigen processing and presentation of peptide antigen | 17/507 | 188/17913 | 0e+00 | 0.0017 | 17 |
| GO:0042593 | glucose homeostasis | 19/507 | 227/17913 | 0e+00 | 0.0017 | 19 |
| GO:0015850 | organic hydroxy compound transport | 19/507 | 228/17913 | 0e+00 | 0.0017 | 19 |
| GO:0033500 | carbohydrate homeostasis | 19/507 | 228/17913 | 0e+00 | 0.0017 | 19 |
| GO:0001666 | response to hypoxia | 25/507 | 354/17913 | 0e+00 | 0.0017 | 25 |
| GO:0070498 | interleukin-1-mediated signaling pathway | 12/507 | 101/17913 | 0e+00 | 0.0017 | 12 |
| GO:0009914 | hormone transport | 23/507 | 311/17913 | 0e+00 | 0.0017 | 23 |
| GO:1901361 | organic cyclic compound catabolic process | 39/507 | 685/17913 | 0e+00 | 0.0017 | 39 |
| GO:0008361 | regulation of cell size | 15/507 | 154/17913 | 0e+00 | 0.0019 | 15 |
| GO:0046700 | heterocycle catabolic process | 37/507 | 641/17913 | 0e+00 | 0.0020 | 37 |
| GO:0044270 | cellular nitrogen compound catabolic process | 37/507 | 642/17913 | 0e+00 | 0.0020 | 37 |
| GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 16/507 | 174/17913 | 0e+00 | 0.0020 | 16 |
| GO:0001738 | morphogenesis of a polarized epithelium | 14/507 | 139/17913 | 0e+00 | 0.0022 | 14 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 16/507 | 176/17913 | 0e+00 | 0.0023 | 16 |
| GO:0032870 | cellular response to hormone stimulus | 37/507 | 647/17913 | 0e+00 | 0.0023 | 37 |
| GO:0030163 | protein catabolic process | 43/507 | 799/17913 | 0e+00 | 0.0023 | 43 |
| GO:0034655 | nucleobase-containing compound catabolic process | 35/507 | 598/17913 | 0e+00 | 0.0023 | 35 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 15/507 | 158/17913 | 0e+00 | 0.0023 | 15 |
| GO:0043488 | regulation of mRNA stability | 15/507 | 158/17913 | 0e+00 | 0.0023 | 15 |
| GO:0007187 | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 16/507 | 178/17913 | 0e+00 | 0.0024 | 16 |
| GO:0010948 | negative regulation of cell cycle process | 24/507 | 344/17913 | 0e+00 | 0.0025 | 24 |
| GO:1903530 | regulation of secretion by cell | 39/507 | 703/17913 | 1e-04 | 0.0025 | 39 |
| GO:0006259 | DNA metabolic process | 49/507 | 964/17913 | 1e-04 | 0.0026 | 49 |
| GO:0034764 | positive regulation of transmembrane transport | 17/507 | 199/17913 | 1e-04 | 0.0026 | 17 |
| GO:0009266 | response to temperature stimulus | 18/507 | 219/17913 | 1e-04 | 0.0026 | 18 |
| GO:0019439 | aromatic compound catabolic process | 37/507 | 655/17913 | 1e-04 | 0.0026 | 37 |
| GO:0050852 | T cell receptor signaling pathway | 16/507 | 180/17913 | 1e-04 | 0.0026 | 16 |
| GO:0051046 | regulation of secretion | 41/507 | 757/17913 | 1e-04 | 0.0026 | 41 |
| GO:0061564 | axon development | 28/507 | 438/17913 | 1e-04 | 0.0026 | 28 |
| GO:0030073 | insulin secretion | 17/507 | 200/17913 | 1e-04 | 0.0026 | 17 |
| GO:0019882 | antigen processing and presentation | 18/507 | 220/17913 | 1e-04 | 0.0026 | 18 |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 15/507 | 162/17913 | 1e-04 | 0.0026 | 15 |
| GO:0007409 | axonogenesis | 26/507 | 393/17913 | 1e-04 | 0.0026 | 26 |
| GO:0060341 | regulation of cellular localization | 45/507 | 863/17913 | 1e-04 | 0.0027 | 45 |
| GO:0008380 | RNA splicing | 28/507 | 440/17913 | 1e-04 | 0.0027 | 28 |
| GO:0043487 | regulation of RNA stability | 15/507 | 163/17913 | 1e-04 | 0.0027 | 15 |
| GO:0070555 | response to interleukin-1 | 16/507 | 183/17913 | 1e-04 | 0.0029 | 16 |
| GO:0060322 | head development | 40/507 | 738/17913 | 1e-04 | 0.0029 | 40 |
| GO:0009611 | response to wounding | 37/507 | 665/17913 | 1e-04 | 0.0032 | 37 |
| GO:0000209 | protein polyubiquitination | 21/507 | 288/17913 | 1e-04 | 0.0032 | 21 |
| GO:0055082 | cellular chemical homeostasis | 37/507 | 666/17913 | 1e-04 | 0.0032 | 37 |
| GO:0044419 | interspecies interaction between organisms | 47/507 | 928/17913 | 1e-04 | 0.0034 | 47 |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | 15/507 | 167/17913 | 1e-04 | 0.0034 | 15 |
| GO:0007420 | brain development | 38/507 | 694/17913 | 1e-04 | 0.0034 | 38 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 37/507 | 669/17913 | 1e-04 | 0.0034 | 37 |
| GO:0050796 | regulation of insulin secretion | 15/507 | 169/17913 | 1e-04 | 0.0038 | 15 |
| GO:2000027 | regulation of animal organ morphogenesis | 19/507 | 250/17913 | 1e-04 | 0.0039 | 19 |
| GO:0019932 | second-messenger-mediated signaling | 24/507 | 360/17913 | 1e-04 | 0.0039 | 24 |
| GO:0006970 | response to osmotic stress | 10/507 | 82/17913 | 1e-04 | 0.0040 | 10 |
| GO:0006091 | generation of precursor metabolites and energy | 30/507 | 502/17913 | 1e-04 | 0.0040 | 30 |
| GO:0010817 | regulation of hormone levels | 30/507 | 503/17913 | 1e-04 | 0.0041 | 30 |
| GO:0043065 | positive regulation of apoptotic process | 36/507 | 652/17913 | 1e-04 | 0.0042 | 36 |
| GO:0050778 | positive regulation of immune response | 42/507 | 809/17913 | 1e-04 | 0.0044 | 42 |
| GO:1901653 | cellular response to peptide | 24/507 | 364/17913 | 1e-04 | 0.0044 | 24 |
| GO:0002218 | activation of innate immune response | 22/507 | 319/17913 | 1e-04 | 0.0044 | 22 |
| GO:0071375 | cellular response to peptide hormone stimulus | 21/507 | 297/17913 | 1e-04 | 0.0044 | 21 |
| GO:0090087 | regulation of peptide transport | 38/507 | 706/17913 | 1e-04 | 0.0044 | 38 |
| GO:0034976 | response to endoplasmic reticulum stress | 19/507 | 254/17913 | 1e-04 | 0.0044 | 19 |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway | 13/507 | 135/17913 | 1e-04 | 0.0044 | 13 |
| GO:0050891 | multicellular organismal water homeostasis | 9/507 | 68/17913 | 1e-04 | 0.0044 | 9 |
| GO:0002758 | innate immune response-activating signal transduction | 21/507 | 298/17913 | 1e-04 | 0.0044 | 21 |
| GO:0031329 | regulation of cellular catabolic process | 42/507 | 814/17913 | 1e-04 | 0.0047 | 42 |
| GO:1901991 | negative regulation of mitotic cell cycle phase transition | 18/507 | 235/17913 | 1e-04 | 0.0047 | 18 |
| GO:0043068 | positive regulation of programmed cell death | 36/507 | 660/17913 | 1e-04 | 0.0048 | 36 |
| GO:0051928 | positive regulation of calcium ion transport | 12/507 | 119/17913 | 1e-04 | 0.0049 | 12 |
| GO:0019221 | cytokine-mediated signaling pathway | 40/507 | 764/17913 | 1e-04 | 0.0049 | 40 |
| GO:0048863 | stem cell differentiation | 18/507 | 237/17913 | 1e-04 | 0.0050 | 18 |
| GO:0071453 | cellular response to oxygen levels | 18/507 | 237/17913 | 1e-04 | 0.0050 | 18 |
| GO:0009408 | response to heat | 14/507 | 158/17913 | 2e-04 | 0.0055 | 14 |
| GO:0016032 | viral process | 42/507 | 822/17913 | 2e-04 | 0.0055 | 42 |
| GO:1901652 | response to peptide | 29/507 | 491/17913 | 2e-04 | 0.0055 | 29 |
| GO:0061013 | regulation of mRNA catabolic process | 15/507 | 178/17913 | 2e-04 | 0.0056 | 15 |
| GO:0033674 | positive regulation of kinase activity | 31/507 | 541/17913 | 2e-04 | 0.0056 | 31 |
| GO:0038061 | NIK/NF-kappaB signaling | 15/507 | 179/17913 | 2e-04 | 0.0058 | 15 |
| GO:0034612 | response to tumor necrosis factor | 20/507 | 284/17913 | 2e-04 | 0.0058 | 20 |
| GO:0006836 | neurotransmitter transport | 18/507 | 241/17913 | 2e-04 | 0.0058 | 18 |
| GO:0036294 | cellular response to decreased oxygen levels | 17/507 | 220/17913 | 2e-04 | 0.0058 | 17 |
| GO:0001819 | positive regulation of cytokine production | 27/507 | 446/17913 | 2e-04 | 0.0059 | 27 |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 25/507 | 399/17913 | 2e-04 | 0.0060 | 25 |
| GO:0002253 | activation of immune response | 35/507 | 647/17913 | 2e-04 | 0.0062 | 35 |
| GO:0044068 | modulation by symbiont of host cellular process | 6/507 | 31/17913 | 2e-04 | 0.0062 | 6 |
| GO:0098657 | import into cell | 39/507 | 751/17913 | 2e-04 | 0.0062 | 39 |
| GO:0044403 | symbiont process | 44/507 | 884/17913 | 2e-04 | 0.0062 | 44 |
| GO:0006354 | DNA-templated transcription, elongation | 11/507 | 106/17913 | 2e-04 | 0.0062 | 11 |
| GO:0022904 | respiratory electron transport chain | 11/507 | 106/17913 | 2e-04 | 0.0062 | 11 |
| GO:0042775 | mitochondrial ATP synthesis coupled electron transport | 10/507 | 89/17913 | 2e-04 | 0.0062 | 10 |
| GO:0071356 | cellular response to tumor necrosis factor | 19/507 | 266/17913 | 2e-04 | 0.0065 | 19 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 47/507 | 968/17913 | 2e-04 | 0.0065 | 47 |
| GO:0009743 | response to carbohydrate | 17/507 | 224/17913 | 2e-04 | 0.0066 | 17 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 17/507 | 224/17913 | 2e-04 | 0.0066 | 17 |
| GO:0042773 | ATP synthesis coupled electron transport | 10/507 | 90/17913 | 2e-04 | 0.0066 | 10 |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 26/507 | 428/17913 | 2e-04 | 0.0067 | 26 |
| GO:0006887 | exocytosis | 43/507 | 862/17913 | 2e-04 | 0.0067 | 43 |
| GO:0009894 | regulation of catabolic process | 45/507 | 916/17913 | 2e-04 | 0.0067 | 45 |
| GO:0006937 | regulation of muscle contraction | 14/507 | 164/17913 | 2e-04 | 0.0069 | 14 |
| GO:0090277 | positive regulation of peptide hormone secretion | 10/507 | 91/17913 | 2e-04 | 0.0071 | 10 |
| GO:0045087 | innate immune response | 44/507 | 893/17913 | 3e-04 | 0.0072 | 44 |
| GO:0000904 | cell morphogenesis involved in differentiation | 34/507 | 632/17913 | 3e-04 | 0.0077 | 34 |
| GO:0010942 | positive regulation of cell death | 37/507 | 710/17913 | 3e-04 | 0.0077 | 37 |
| GO:0002790 | peptide secretion | 32/507 | 582/17913 | 3e-04 | 0.0078 | 32 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 26/507 | 434/17913 | 3e-04 | 0.0079 | 26 |
| GO:0002791 | regulation of peptide secretion | 28/507 | 483/17913 | 3e-04 | 0.0079 | 28 |
| GO:0071407 | cellular response to organic cyclic compound | 30/507 | 533/17913 | 3e-04 | 0.0080 | 30 |
| GO:0098810 | neurotransmitter reuptake | 5/507 | 22/17913 | 3e-04 | 0.0085 | 5 |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 10/507 | 94/17913 | 3e-04 | 0.0087 | 10 |
| GO:0071456 | cellular response to hypoxia | 16/507 | 210/17913 | 3e-04 | 0.0087 | 16 |
| GO:0008217 | regulation of blood pressure | 14/507 | 169/17913 | 3e-04 | 0.0087 | 14 |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 14/507 | 169/17913 | 3e-04 | 0.0087 | 14 |
| GO:0031349 | positive regulation of defense response | 29/507 | 512/17913 | 3e-04 | 0.0088 | 29 |
| GO:0043269 | regulation of ion transport | 34/507 | 639/17913 | 3e-04 | 0.0088 | 34 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 22/507 | 344/17913 | 3e-04 | 0.0089 | 22 |
| GO:0000398 | mRNA splicing, via spliceosome | 22/507 | 344/17913 | 3e-04 | 0.0089 | 22 |
| GO:1901988 | negative regulation of cell cycle phase transition | 18/507 | 254/17913 | 3e-04 | 0.0089 | 18 |
| GO:0006119 | oxidative phosphorylation | 12/507 | 131/17913 | 3e-04 | 0.0089 | 12 |
| GO:0030177 | positive regulation of Wnt signaling pathway | 14/507 | 170/17913 | 3e-04 | 0.0089 | 14 |
| GO:0044772 | mitotic cell cycle phase transition | 31/507 | 565/17913 | 4e-04 | 0.0092 | 31 |
| GO:0007417 | central nervous system development | 45/507 | 935/17913 | 4e-04 | 0.0092 | 45 |
| GO:0002757 | immune response-activating signal transduction | 31/507 | 567/17913 | 4e-04 | 0.0097 | 31 |
| GO:0034767 | positive regulation of ion transmembrane transport | 13/507 | 152/17913 | 4e-04 | 0.0098 | 13 |
| GO:1903706 | regulation of hemopoiesis | 27/507 | 468/17913 | 4e-04 | 0.0099 | 27 |
| GO:0000375 | RNA splicing, via transesterification reactions | 22/507 | 348/17913 | 4e-04 | 0.0099 | 22 |